SURVIVAL IN A BAD NEIGHBORHOOD: PANCREATIC ISLETS IN CYSTIC FIBROSIS

In cystic fibrosis (CF), ductal plugging and acinar loss result in rapid decline of exocrine pancreatic function. This destructive process results in remodeled islets, with only a modest reduction in insulin producing β cells. However, β-cell function is profoundly impaired, with decreased insulin r...

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Vydáno v:J Endocrinol
Hlavní autoři: Norris, Andrew W., Ode, Katie Larson, Merjaneh, Lina, Sanda, Srinath, Yi, Yaling, Sun, Xingshen, Engelhardt, John F., Hull, Rebecca L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675675/
https://ncbi.nlm.nih.gov/pubmed/30759072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0468
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