Proximal Tubular Cannabinoid-1 Receptor Regulates Obesity-Induced CKD

Obesity-related structural and functional changes in the kidney develop early in the course of obesity and occur independently of hypertension, diabetes, and dyslipidemia. Activating the renal cannabinoid-1 receptor (CB(1)R) induces nephropathy, whereas CB(1)R blockade improves kidney function. Whet...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Udi, Shiran, Hinden, Liad, Earley, Brian, Drori, Adi, Reuveni, Noa, Hadar, Rivka, Cinar, Resat, Nemirovski, Alina, Tam, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2017
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698062/
https://ncbi.nlm.nih.gov/pubmed/28860163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016101085
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