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Modulation of Renal GLUT2 by the Cannabinoid-1 Receptor: Implications for the Treatment of Diabetic Nephropathy
Altered glucose reabsorption via the facilitative glucose transporter 2 (GLUT2) during diabetes may lead to renal proximal tubule cell (RPTC) injury, inflammation, and interstitial fibrosis. These pathologies are also triggered by activating the cannabinoid-1 receptor (CB(1)R), which contributes to...
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發表在: | J Am Soc Nephrol |
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Main Authors: | , , , , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
American Society of Nephrology
2018
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791066/ https://ncbi.nlm.nih.gov/pubmed/29030466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017040371 |
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