Modulation of Renal GLUT2 by the Cannabinoid-1 Receptor: Implications for the Treatment of Diabetic Nephropathy

Altered glucose reabsorption via the facilitative glucose transporter 2 (GLUT2) during diabetes may lead to renal proximal tubule cell (RPTC) injury, inflammation, and interstitial fibrosis. These pathologies are also triggered by activating the cannabinoid-1 receptor (CB(1)R), which contributes to...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Hinden, Liad, Udi, Shiran, Drori, Adi, Gammal, Asaad, Nemirovski, Alina, Hadar, Rivka, Baraghithy, Saja, Permyakova, Anna, Geron, Matan, Cohen, Merav, Tsytkin-Kirschenzweig, Sabina, Riahi, Yael, Leibowitz, Gil, Nahmias, Yaakov, Priel, Avi, Tam, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791066/
https://ncbi.nlm.nih.gov/pubmed/29030466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017040371
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