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Dual inhibition of cannabinoid CB(1) receptor and inducible NOS attenuates obesity‐induced chronic kidney disease
BACKGROUND AND PURPOSE: Obesity, an important risk factor for developing chronic kidney disease (CKD), affects the kidneys by two main molecular signalling pathways: the endocannabinoid/CB(1) receptor system, whose activation in obesity promotes renal inflammation, fibrosis, and injury, and the indu...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6976880/ https://ncbi.nlm.nih.gov/pubmed/31454063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14849 |
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