Dual inhibition of cannabinoid CB(1) receptor and inducible NOS attenuates obesity‐induced chronic kidney disease

BACKGROUND AND PURPOSE: Obesity, an important risk factor for developing chronic kidney disease (CKD), affects the kidneys by two main molecular signalling pathways: the endocannabinoid/CB(1) receptor system, whose activation in obesity promotes renal inflammation, fibrosis, and injury, and the indu...

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Pubblicato in:Br J Pharmacol
Autori principali: Udi, Shiran, Hinden, Liad, Ahmad, Majdoleen, Drori, Adi, Iyer, Malliga R., Cinar, Resat, Herman‐Edelstein, Michal, Tam, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976880/
https://ncbi.nlm.nih.gov/pubmed/31454063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14849
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