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Programmed Cell Death Protein Ligand-1 (PD-L1) Silencing with Polyethylenimine-Dermatan Sulfate Complex for Dual Inhibition of Melanoma Growth

Programmed cell death protein-1 (PD-1) is a prominent immune checkpoint receptor interacting with its ligand, programmed cell death protein ligand-1 (PD-L1, B7-H1). The PD-1/PD-L1 interaction induces functional exhaustion of tumor-reactive cytotoxic T cells and, thus, interferes with antitumor T-cel...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Kwak, Gijung, Kim, Dongkyu, Nam, Gi-hoon, Wang, Sun Young, Kim, In-San, Kim, Sun Hwa, Kwon, Ick-Chan, Yeo, Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697980/
https://ncbi.nlm.nih.gov/pubmed/28985469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b04717
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