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Polyethylenimine-dermatan sulfate complex, a bioactive biomaterial with unique toxicity to CD146-positive cancer cells

We report unique bioactivity of a polycation-polyanion complex with potential utility for cancer therapy. A complex of disulfide-crosslinked polyethyleneimine (CLPEI), a polycation used for gene complexation, and dermatan sulfate (DS), an anionic polysaccharide to shield excessive cationic charge of...

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Detalhes bibliográficos
Publicado no:ACS Biomater Sci Eng
Main Authors: Kim, Bieong-Kil, Kim, Dongkyu, Kwak, Gijung, Yhee, Ji Young, Kwon, Ick-Chan, Kim, Sun Hwa, Yeo, Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813828/
https://ncbi.nlm.nih.gov/pubmed/29457127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.7b00207
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