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Two Dermatan Sulfate Epimerases Form Iduronic Acid Domains in Dermatan Sulfate

A second dermatan sulfate epimerase (DS-epi2) was identified as a homolog of the first epimerase (DS-epi1), which was previously described by our group. DS-epi2 is 1,222 amino acids long and has an ∼700-amino acid N-terminal epimerase domain that is highly conserved between the two enzymes. In addit...

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Main Authors: Pacheco, Benny, Malmström, Anders, Maccarana, Marco
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665100/
https://ncbi.nlm.nih.gov/pubmed/19188366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809339200
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