Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

Increasing evidence suggests that apoptosis may be the underlying cell death mechanism in the selective loss of dopaminergic neurons in Parkinson's disease. Because the inhibition of caspases provides only partial protection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/1-methyl-4-phenylp...

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Библиографические подробности
Главные авторы: Xia, Xu Gang, Harding, Thomas, Weller, Michael, Bieneman, Alison, Uney, James B., Schulz, Jörg B.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2001
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC56978/
https://ncbi.nlm.nih.gov/pubmed/11504916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181182298
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