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Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

Increasing evidence suggests that apoptosis may be the underlying cell death mechanism in the selective loss of dopaminergic neurons in Parkinson's disease. Because the inhibition of caspases provides only partial protection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/1-methyl-4-phenylp...

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Detalhes bibliográficos
Main Authors: Xia, Xu Gang, Harding, Thomas, Weller, Michael, Bieneman, Alison, Uney, James B., Schulz, Jörg B.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC56978/
https://ncbi.nlm.nih.gov/pubmed/11504916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181182298
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