Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

Increasing evidence suggests that apoptosis may be the underlying cell death mechanism in the selective loss of dopaminergic neurons in Parkinson's disease. Because the inhibition of caspases provides only partial protection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/1-methyl-4-phenylp...

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Bibliografiska uppgifter
Huvudupphovsmän: Xia, Xu Gang, Harding, Thomas, Weller, Michael, Bieneman, Alison, Uney, James B., Schulz, Jörg B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2001
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC56978/
https://ncbi.nlm.nih.gov/pubmed/11504916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181182298
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