TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis

The 18 kDa translocator protein (TSPO) is a ubiquitous conserved outer mitochondrial membrane protein implicated in numerous cell and tissue functions, including steroid hormone biosynthesis, respiration, cell proliferation, and apoptosis. TSPO binds with high affinity to cholesterol and numerous co...

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Dettagli Bibliografici
Pubblicato in:Biochem J
Autori principali: Owen, David R., Fan, Jinjiang, Campioli, Enrico, Venugopal, Sathvika, Midzak, Andrew, Daly, Edward, Harlay, Aline, Issop, Leeyah, Libri, Vincenzo, Kalogiannopoulou, Dimitra, Oliver, Eduardo, Gallego-Colon, Enrique, Colasanti, Alessandro, Huson, Les, Rabiner, Eugenii A., Suppiah, Puvan, Essagian, Charles, Matthews, Paul M., Papadopoulos, Vassilios
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2017
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697202/
https://ncbi.nlm.nih.gov/pubmed/29074640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170648
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