Identification of a Dynamic Mitochondrial Protein Complex Driving Cholesterol Import, Trafficking, and Metabolism to Steroid Hormones

Steroid hormones are critical for organismal development and health. The rate-limiting step in steroidogenesis is the transport of cholesterol from the outer mitochondrial membrane (OMM) to the cytochrome P450 enzyme CYP11A1 in the inner mitochondrial membrane (IMM). Cholesterol transfer occurs thro...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Endocrinol
Auteurs principaux: Rone, Malena B., Midzak, Andrew S., Issop, Leeyah, Rammouz, Georges, Jagannathan, Sathvika, Fan, Jinjiang, Ye, Xiaoying, Blonder, Josip, Veenstra, Timothy, Papadopoulos, Vassilios
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2012
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416962/
https://ncbi.nlm.nih.gov/pubmed/22973050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1159
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