Identification of a Dynamic Mitochondrial Protein Complex Driving Cholesterol Import, Trafficking, and Metabolism to Steroid Hormones

Steroid hormones are critical for organismal development and health. The rate-limiting step in steroidogenesis is the transport of cholesterol from the outer mitochondrial membrane (OMM) to the cytochrome P450 enzyme CYP11A1 in the inner mitochondrial membrane (IMM). Cholesterol transfer occurs thro...

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Bibliografski detalji
Izdano u:Mol Endocrinol
Glavni autori: Rone, Malena B., Midzak, Andrew S., Issop, Leeyah, Rammouz, Georges, Jagannathan, Sathvika, Fan, Jinjiang, Ye, Xiaoying, Blonder, Josip, Veenstra, Timothy, Papadopoulos, Vassilios
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2012
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416962/
https://ncbi.nlm.nih.gov/pubmed/22973050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1159
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