Identification of a Dynamic Mitochondrial Protein Complex Driving Cholesterol Import, Trafficking, and Metabolism to Steroid Hormones

Steroid hormones are critical for organismal development and health. The rate-limiting step in steroidogenesis is the transport of cholesterol from the outer mitochondrial membrane (OMM) to the cytochrome P450 enzyme CYP11A1 in the inner mitochondrial membrane (IMM). Cholesterol transfer occurs thro...

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Vydáno v:Mol Endocrinol
Hlavní autoři: Rone, Malena B., Midzak, Andrew S., Issop, Leeyah, Rammouz, Georges, Jagannathan, Sathvika, Fan, Jinjiang, Ye, Xiaoying, Blonder, Josip, Veenstra, Timothy, Papadopoulos, Vassilios
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416962/
https://ncbi.nlm.nih.gov/pubmed/22973050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1159
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