TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis

The 18 kDa translocator protein (TSPO) is a ubiquitous conserved outer mitochondrial membrane protein implicated in numerous cell and tissue functions, including steroid hormone biosynthesis, respiration, cell proliferation, and apoptosis. TSPO binds with high affinity to cholesterol and numerous co...

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Veröffentlicht in:Biochem J
Hauptverfasser: Owen, David R., Fan, Jinjiang, Campioli, Enrico, Venugopal, Sathvika, Midzak, Andrew, Daly, Edward, Harlay, Aline, Issop, Leeyah, Libri, Vincenzo, Kalogiannopoulou, Dimitra, Oliver, Eduardo, Gallego-Colon, Enrique, Colasanti, Alessandro, Huson, Les, Rabiner, Eugenii A., Suppiah, Puvan, Essagian, Charles, Matthews, Paul M., Papadopoulos, Vassilios
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2017
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697202/
https://ncbi.nlm.nih.gov/pubmed/29074640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170648
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