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A Small-Molecule Inducible Synthetic Circuit for Control of the SOS Gene Network without DNA Damage

[Image: see text] The bacterial SOS stress-response pathway is a pro-mutagenic DNA repair system that mediates bacterial survival and adaptation to genotoxic stressors, including antibiotics and UV light. The SOS pathway is composed of a network of genes under the control of the transcriptional repr...

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Detalhes bibliográficos
Publicado no:ACS Synth Biol
Main Authors: Kubiak, Jeffrey M., Culyba, Matthew J., Liu, Monica Yun, Mo, Charlie Y., Goulian, Mark, Kohli, Rahul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696648/
https://ncbi.nlm.nih.gov/pubmed/28826208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.7b00108
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