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Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network

Biochemical pathways are often genetically encoded as simple transcription regulation networks, where one transcription factor regulates the expression of multiple genes in a pathway. The relative timing of each promoter’s activation and shut-off within the network can impact physiology. In the DNA...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS Genet
Päätekijät: Culyba, Matthew J., Kubiak, Jeffrey M., Mo, Charlie Y., Goulian, Mark, Kohli, Rahul M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999292/
https://ncbi.nlm.nih.gov/pubmed/29856734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007405
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