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Specificity Determinants for Autoproteolysis of LexA, a Key Regulator of Bacterial SOS Mutagenesis

[Image: see text] Bacteria utilize the tightly regulated stress response (SOS) pathway to respond to a variety of genotoxic agents, including antimicrobials. Activation of the SOS response is regulated by a key repressor-protease, LexA, which undergoes autoproteolysis in the setting of stress, resul...

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Detalhes bibliográficos
Main Authors: Mo, Charlie Y., Birdwell, L. Dillon, Kohli, Rahul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030785/
https://ncbi.nlm.nih.gov/pubmed/24779472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500026e
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