Ginkgetin induces autophagic cell death through p62/SQSTM1-mediated autolysosome formation and redox setting in non-small cell lung cancer

Promoting cell death by autophagy could be a novel treatment for cancer. The major player in autophagy, p62, serves as a good therapeutic target. Ginkgetin, a biflavonoid from Ginkgo biloba leaves, exhibited promising anticancer activity in non-small cell lung cancer cell lines, with an IC50 lower t...

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Publicat a:Oncotarget
Autors principals: Lou, Jian-Shu, Bi, Wen-Chuan, Chan, Gallant K.L, Jin, Yan, Wong, Chau-Wing, Zhou, Zhong-Yu, Wang, Huai-You, Yao, Ping, Dong, Tina T.X., Tsim, Karl W.K.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696249/
https://ncbi.nlm.nih.gov/pubmed/29190983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21862
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