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An inhibition of p62/SQSTM1 caused autophagic cell death of several human carcinoma cells
p62/SQSTM1 (p62) is a multifunctional protein implicated in several signal transduction pathways and selectively degraded by autophagy, a process for lysosomal degradation of both protein and organelle. p62 was also recently reported to be overexpressed in various malignancies and its inhibition to...
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| Veröffentlicht in: | Cancer Sci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317843/ https://ncbi.nlm.nih.gov/pubmed/24618016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12396 |
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