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A functional role for Tsix transcription in blocking Xist RNA accumulation but not in X-chromosome choice

In female mammals, up-regulation of Xist triggers X-chromosome inactivation in cis. Up-regulation is inhibited by sequences 3′ to Xist contained within the antisense locus, Tsix. Inhibition could depend on transcription of Tsix and/or on DNA elements therein. Here we test the role of Tsix transcript...

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Библиографические подробности
Главные авторы: Stavropoulos, Nicholas, Lu, Naifung, Lee, Jeannie T.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC56944/
https://ncbi.nlm.nih.gov/pubmed/11481444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171243598
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