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A functional role for Tsix transcription in blocking Xist RNA accumulation but not in X-chromosome choice
In female mammals, up-regulation of Xist triggers X-chromosome inactivation in cis. Up-regulation is inhibited by sequences 3′ to Xist contained within the antisense locus, Tsix. Inhibition could depend on transcription of Tsix and/or on DNA elements therein. Here we test the role of Tsix transcript...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC56944/ https://ncbi.nlm.nih.gov/pubmed/11481444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171243598 |
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