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The coreceptor mutation CCR5Δ32 influences the dynamics of HIV epidemics and is selected for by HIV
We explore the impact of a host genetic factor on heterosexual HIV epidemics by using a deterministic mathematical model. A protective allele unequally distributed across populations is exemplified in our models by the 32-bp deletion in the host-cell chemokine receptor CCR5, CCR5Δ32. Individuals hom...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC56941/ https://ncbi.nlm.nih.gov/pubmed/11517319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181325198 |
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