HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem cell transplantation

HIV-1 cure remains elusive with only one reported case a decade ago(1,2.) Termed the “Berlin Patient”, the individual underwent 2 allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) procedures using a donor with a homozygous mutation in the HIV coreceptor CCR5 (CCR5Δ32/Δ32) to treat his a...

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Publicado en:Nature
Autores principales: Gupta, Ravindra K, Abdul-jawad, Sultan, McCoy, Laura E, Mok, Hoi Ping, Peppa, Dimitra, Salgado, Maria, Martinez-Picado, Javier, Nijhuis, Monique, Wensing, Annemarie M.J., Lee, Helen, Grant, Paul, Nastouli, Eleni, Lambert, Jonathan, Pace, Matthew, Salasc, Fanny, Monit, Christopher, Innes, Andrew, Muir, Luke, Waters, Laura, Frater, John, Lever, Andrew ML, Edwards, SG, Gabriel, Ian H, Olavarria, Eduardo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275870/
https://ncbi.nlm.nih.gov/pubmed/30836379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1027-4
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