The Case for Selection at CCR5-Δ32

The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Δ32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Δ32 arose within the past 1,000 y and rose to its present high frequency (5%–14%) in Europe as a result of strong positive sel...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sabeti, Pardis C, Walsh, Emily, Schaffner, Steve F, Varilly, Patrick, Fry, Ben, Hutcheson, Holli B, Cullen, Mike, Mikkelsen, Tarjei S, Roy, Jessica, Patterson, Nick, Cooper, Richard, Reich, David, Altshuler, David, O'Brien, Stephen, Lander, Eric S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2005
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1275522/
https://ncbi.nlm.nih.gov/pubmed/16248677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030378
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