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Blockade of alcohol escalation and “relapse” drinking by pharmacological FAAH inhibition in male and female C57BL/6J mice

BACKGROUND: Anandamide (AEA)-dependent signaling is regulated by the catabolic enzyme fatty acid amide hydrolase (FAAH). Several lines of evidence have demonstrated that FAAH and AEA are involved in the behavioral effects of alcohol. Therefore, we investigated whether a selective FAAH inhibitor, URB...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Zhou, Yan, Schwartz, Benjamin I, Giza, Joanna, Gross, Steven S, Lee, Francis S, Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693682/
https://ncbi.nlm.nih.gov/pubmed/28730283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4691-9
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