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Persistent escalation of alcohol drinking in C57BL/6J mice with intermittent access to 20% ethanol

BACKGROUND: Intermittent access to drugs of abuse, as opposed to continuous access, is hypothesized to induce a kindling-type transition from moderate to escalated use, leading to dependence. Intermittent 24-hour cycles of ethanol access and deprivation can generate high levels of voluntary ethanol...

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Detalhes bibliográficos
Main Authors: Hwa, Lara S., Chu, Adam, Levinson, Sally A., Kayyali, Tala M., DeBold, Joseph F., Miczek, Klaus A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166538/
https://ncbi.nlm.nih.gov/pubmed/21631540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01545.x
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