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Effects of withdrawal from chronic escalating-dose binge cocaine on conditioned place preference to cocaine and striatal preproenkephalin mRNA in C57BL/6J mice

Relapse is a serious problem for the effective treatment of cocaine addiction. RATIONALE: Examining cocaine re-exposure-induced behavioral and neurobiological alterations following chronic escalating-dose binge cocaine administration and withdrawal may provide insight into the neurobiological basis...

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Detalhes bibliográficos
Main Authors: Zhang, Yong, Schlussman, Stefan D., Butelman, Eduardo R., Ho, Ann, Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979702/
https://ncbi.nlm.nih.gov/pubmed/22504589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.03.021
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