Effects of cocaine place conditioning, chronic escalating-dose “binge” pattern cocaine administration and acute withdrawal on orexin/hypocretin and preprodynorphin gene expressions in lateral hypothalamus of Fischer and Sprague-Dawley rats

Recent evidence suggests an important role for hypothalamic orexins/hypocretins in modulation of drug reward and addiction-like behaviors in rodents. Our recent study has shown that the aversive state of arousal during acute morphine withdrawal is associated with increased orexin gene expression in...

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Bibliografiske detaljer
Main Authors: Zhou, Yan, Cui, Cai-Lian, Schlussman, Stefan D., Choi, Jason C., Ho, Ann, Han, Ji-Sheng, Kreek, Mary Jeanne
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494861/
https://ncbi.nlm.nih.gov/pubmed/18436386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.03.023
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