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Acute Withdrawal from Chronic Escalating-Dose Binge Cocaine Administration Alters Kappa Opioid Receptor Stimulation of [(35)S]GTPγS Binding in the Rat Ventral Tegmental Area

There is evidence that the kappa opioid system plays an important role in cocaine addiction and that chronic cocaine administration and withdrawal from chronic cocaine alter kappa opioid receptor (KOPr) density. The present study employed in situ [(35)S]GTPγS binding autoradiography to measure KOPr-...

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Detalhes bibliográficos
Main Authors: Piras, A. P., Zhou, Y., Schlussman, S. D., Ho, A., Kreek, M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716394/
https://ncbi.nlm.nih.gov/pubmed/20452406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.04.060
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