EXTH-55. REPURPOSING THERAPEUTICS IN PATIENT-DERIVED GLIOMAS AND AN IDH1 MUTANT GLIOMA MODEL

Malignant glioma is the most common primary brain tumor in adults, where ~70% of newly diagnosed cases represent glioblastoma. As a result, development of novel therapies has focused on this tumor rather than lower-grade gliomas. Mutations of isocitrate dehydrogenase (IDH) genes have been found in ~...

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Vydáno v:Neuro Oncol
Hlavní autoři: Schmidt, Christin, Chen, Steven, IIkhanizadeh, Shirin, Sabelstrom, Hanna, Yuan, Edith, Ding, Andy, Weiss, William, Berger, Mitchel S, Arkin, Michelle, Persson, Anders
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693161/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.347
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