STEM-11. A MAPK-DRIVEN miR-124-SOX9 AXIS IS CRITICAL FOR STEM CELL MAINTENANCE, PROGRESSION, AND THERAPY-RESISTANCE IN GLIOBLASTOMA

Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor. Genetic alterations in growth factor signaling pathways are found in 90% of GBMs. Advances in developmental and glioma biology suggest that common down-stream effector molecules in growth factor signaling pathways ar...

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Publicado no:Neuro Oncol
Main Authors: Sabelstrom, Hanna, Petri, Rebecca, Shchors, Ksenya, Jandial, Rahul, Sacheva, Rohit, Masic, Selma, Yuan, Edith, Fenster, Trenten, Nicolaides, Theo, IIkhanizadeh, Shirin, Berger, Mitchel S, Snyder, Evan, Weiss, William, Jakobsson, Johan, Persson, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692894/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.927
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