Investigating molecular crowding within nuclear pores using polarization-PALM

The key component of the nuclear pore complex (NPC) controlling permeability, selectivity, and the speed of nucleocytoplasmic transport is an assembly of natively unfolded polypeptides, which contain phenylalanine-glycine (FG) binding sites for nuclear transport receptors. The architecture and dynam...

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Bibliographic Details
Published in:eLife
Main Authors: Fu, Guo, Tu, Li-Chun, Zilman, Anton, Musser, Siegfried M
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2017
Subjects:
Structural Biology and Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693140/
https://ncbi.nlm.nih.gov/pubmed/28949296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28716
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