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In vivo analysis of protein crowding within the nuclear pore complex in interphase and mitosis

The central channel of the nuclear pore complex (NPC) is occupied by non-structured polypeptides with a high content of Phe-Gly (FG) motifs. This protein-rich environment functions as an entropic barrier that prevents the passage of molecules, as well as the binding sites for karyopherins, to regula...

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Vydáno v:Sci Rep
Hlavní autoři: Konishi, Hide A., Asai, Suguru, Watanabe, Tomonobu M., Yoshimura, Shige H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515885/
https://ncbi.nlm.nih.gov/pubmed/28720791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05959-w
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