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IMMU-05. IMMUNE STIMULATION AND IMMUNE CHECKPOINT INHIBITION PROVIDED BY A SINGLE AGENT: AN ONCOLYTIC HSV EXPRESSING A scFv ANTIBODY AGAINST PD-1
Glioblastoma multiforme (GBM), a deadly brain tumor, is resistant to current standard of care treatments including surgery and chemo-radiotherapy. This cancer is also characterized by a highly immunosuppressive microenvironment. Immune checkpoints inhibitors (such as the antiPD-1 antibody) efficient...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693095/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.464 |
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