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IMMU-05. IMMUNE STIMULATION AND IMMUNE CHECKPOINT INHIBITION PROVIDED BY A SINGLE AGENT: AN ONCOLYTIC HSV EXPRESSING A scFv ANTIBODY AGAINST PD-1

Glioblastoma multiforme (GBM), a deadly brain tumor, is resistant to current standard of care treatments including surgery and chemo-radiotherapy. This cancer is also characterized by a highly immunosuppressive microenvironment. Immune checkpoints inhibitors (such as the antiPD-1 antibody) efficient...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Passaro, Carmela, Alayo, Quazim, Nakashima, Hiroshi, Chiocca, E Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693095/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.464
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