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TMIC-26. IMMUNOMODULATION WITH TEMOZOLOMIDE TO IMPROVE EFFICACY OF IMMUNE CHECKPOINT INHIBITION FOR THE TREATMENT OF GLIOBLASTOMA

Immune checkpoint inhibitors are under active investigation as novel strategies for the treatment of newly diagnosed glioblastoma (GBM). Due to the effects of temozolomide (TMZ) on host immunity, we hypothesize that dose and timing of TMZ will impact efficacy of immune checkpoint inhibition with PD-...

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Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Karachi, Aida, Dastmalchi, Farhad, Yang, Changlin, Huang, Jianping, Mitchell, Duane, Rahman, Maryam
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692988/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1015
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