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TMIC-26. IMMUNOMODULATION WITH TEMOZOLOMIDE TO IMPROVE EFFICACY OF IMMUNE CHECKPOINT INHIBITION FOR THE TREATMENT OF GLIOBLASTOMA

Immune checkpoint inhibitors are under active investigation as novel strategies for the treatment of newly diagnosed glioblastoma (GBM). Due to the effects of temozolomide (TMZ) on host immunity, we hypothesize that dose and timing of TMZ will impact efficacy of immune checkpoint inhibition with PD-...

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Publicat a:Neuro Oncol
Autors principals: Karachi, Aida, Dastmalchi, Farhad, Yang, Changlin, Huang, Jianping, Mitchell, Duane, Rahman, Maryam
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692988/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1015
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