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IMMU-45. DOSE MODULATION OF TEMOZOLOMIDE HAVE DISTINCT EFFECTS ON HOST RESPONSE TO PD-1 BLOCKADE

INTRODUCTION: Temozolomide is known to affect efficacy of immunotherapy due to effects on the tumor microenvironment and host immune cell function. The effects of temozolomide dosing on efficacy of immune checkpoint inhibition is unknown. HYPOTHESIS: Dose modification of temozolomide modulates host...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Karachi, Aida, Dastmalchi, Farhad, Yang, Changlin, Huang, Jianping, Sayour, Elias, Mitchell, Duane, Rahman, Maryam
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216439/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.548
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