IMMU-45. DOSE MODULATION OF TEMOZOLOMIDE HAVE DISTINCT EFFECTS ON HOST RESPONSE TO PD-1 BLOCKADE

INTRODUCTION: Temozolomide is known to affect efficacy of immunotherapy due to effects on the tumor microenvironment and host immune cell function. The effects of temozolomide dosing on efficacy of immune checkpoint inhibition is unknown. HYPOTHESIS: Dose modification of temozolomide modulates host...

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Publicat a:Neuro Oncol
Autors principals: Karachi, Aida, Dastmalchi, Farhad, Yang, Changlin, Huang, Jianping, Sayour, Elias, Mitchell, Duane, Rahman, Maryam
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216439/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.548
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