CSIG-17. TARGETING THE KYNURENINE PATHWAY OF TRYPTOPHAN METABOLISM IN PATIENT-DERIVED MELANOMA BRAIN METASTATIC CELLS

BACKGROUND: Proportionate to their incidence, melanoma lesions have the greatest propensity to form brain metastases. A paucity of treatment options for metastatic brain tumors has led to poor patient prognosis and a dire need for novel therapies. Mounting evidence favors that the kynurenine pathway...

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Vydáno v:Neuro Oncol
Hlavní autoři: Fadel, Hassan A, Michelhaugh, Sharon K, Guastella, Anthony R, Kiousis, Sam, Mittal, Sandeep
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692978/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.211
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