Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma

Increasing evidence demonstrates the immunosuppressive kynurenine pathway’s (KP) role in the pathophysiology of human gliomas. To study the KP in vivo, we used the noninvasive molecular imaging tracer α-[(11)C]-methyl-l-tryptophan (AMT). The AMT-positron emission tomography (PET) has shown high upta...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Imaging
Main Authors: Guastella, Anthony R., Michelhaugh, Sharon K., Klinger, Neil V., Kupsky, William J., Polin, Lisa A., Muzik, Otto, Juhász, Csaba, Mittal, Sandeep
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887573/
https://ncbi.nlm.nih.gov/pubmed/27151136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1536012116644881
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