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TMIC-40. ASSESSMENT OF THE KYNURENINE PATHWAY OF TRYPTOPHAN METABOLISM IN PRIMARY BRAIN TUMORS

BACKGROUND: There is a mounting body of data supporting the role of tryptophan metabolism via the kynurenine pathway (KP) in the pathophysiology of primary brain tumors. In the current study, we examined the differences in KP protein expression, as well as pharmacological inhibition of the KP in WHO...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Guastella, Anthony R, Kiousis, Sam, Klinger, Neil V, Fadel, Hassan A, Kupsky, William, Michelhaugh, Sharon K, Mittal, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692440/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1028
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