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CSIG-17. TARGETING THE KYNURENINE PATHWAY OF TRYPTOPHAN METABOLISM IN PATIENT-DERIVED MELANOMA BRAIN METASTATIC CELLS

BACKGROUND: Proportionate to their incidence, melanoma lesions have the greatest propensity to form brain metastases. A paucity of treatment options for metastatic brain tumors has led to poor patient prognosis and a dire need for novel therapies. Mounting evidence favors that the kynurenine pathway...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Fadel, Hassan A, Michelhaugh, Sharon K, Guastella, Anthony R, Kiousis, Sam, Mittal, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692978/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.211
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