PDTM-06. TARGETED CATALYTIC INHIBITION OF EZH2 SYNERGIZES WITH LOW-DOSE PANOBINOSTAT IN MALIGNANT RHABDOID TUMOR

Malignant Rhabdoid Tumor (MRT) is a rare pediatric cancer predominant in the kidney and CNS that is resistant to current treatment regimes. MRT is genetically characterized by homozygous inactivation of SMARCB1, a core subunit of the SWI/SNF chromatin-remodeling complex. Next-generation sequencing d...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Popovski, Dean, Cochrane, Catherine R, Algar, Elizabeth M, Szczepny, Anette, Jayasekara, W Samantha, Ashley, David M, Downie, Peter, Watkins, D Neil, Cain, Jason E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692955/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.771
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados