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PATH-02. USE OF RNAseq TO IDENTIFY TUMOR CELL AND MICROENVIRONMENT FACTORS ASSOCIATED WITH IMMUNE CYTOLYTIC ACTIVITY IN GLIOBLASTOMA
BACKGROUND: Determinants of immune activation in glioblastoma (GBM) are poorly understood, providing little immunotherapeutic guidance. Using a validated gene expression signature of intratumoral immune cytolytic activity (CYT; Rooney et al, Cell 2015), we sought to determine which tumor-intrinsic a...
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| Publié dans: | Neuro Oncol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692802/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.693 |
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