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PATH-02. USE OF RNAseq TO IDENTIFY TUMOR CELL AND MICROENVIRONMENT FACTORS ASSOCIATED WITH IMMUNE CYTOLYTIC ACTIVITY IN GLIOBLASTOMA

BACKGROUND: Determinants of immune activation in glioblastoma (GBM) are poorly understood, providing little immunotherapeutic guidance. Using a validated gene expression signature of intratumoral immune cytolytic activity (CYT; Rooney et al, Cell 2015), we sought to determine which tumor-intrinsic a...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Bagley, Stephen J, O’Rourke, Donald M, Brem, Steven, Linette, Gerald P, Desai, Arati S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692802/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.693
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