PATH-40. TARGETED NEXT GENERATION SEQUENCING (NGS) OF YOUNG ADULTS WITH ISOCITRATE-DEHYDROGENASE WILD-TYPE GLIOBLASTOMA (IDH-WT GBM) REVEALS NEGATIVE PROGNOSTIC IMPACT OF EPIDERMAL GROWTH FACTOR RECEPTOR AMPLIFICATION (EGFRAMP)

BACKGROUND: Young adults with IDH-WT GBM represent a rare, understudied population compared to pediatric, IDH-mutant, or typical (elderly) GBM. We aimed to explore clinically detected genomic alterations in this population and their prognostic impact. METHODS: We identified patients ages 21 45 with...

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Опубликовано в: :Neuro Oncol
Главные авторы: Hoffman, Daniel, Abdullah, Kalil, Binder, Zev, O’Rourke, Donald, Desai, Arati, Morrissette, Jennifer, Brem, Steven, Bagley, Stephen
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
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Abstracts
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216849/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.696
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