PATH-02. USE OF RNAseq TO IDENTIFY TUMOR CELL AND MICROENVIRONMENT FACTORS ASSOCIATED WITH IMMUNE CYTOLYTIC ACTIVITY IN GLIOBLASTOMA

BACKGROUND: Determinants of immune activation in glioblastoma (GBM) are poorly understood, providing little immunotherapeutic guidance. Using a validated gene expression signature of intratumoral immune cytolytic activity (CYT; Rooney et al, Cell 2015), we sought to determine which tumor-intrinsic a...

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Pubblicato in:Neuro Oncol
Autori principali: Bagley, Stephen J, O’Rourke, Donald M, Brem, Steven, Linette, Gerald P, Desai, Arati S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692802/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.693
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