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STEM-04. MECHANISM OF DYSREGULATION AND EFFICACY OF PHARMACOLOGICALLY TARGETING THE APC/C IN GLIOBLASTOMA

Glioblastoma (GBM) is the most lethal type of primary brain tumor with the common length of survival after diagnosis at only 12 to 15 months. One of the causes of poor patient outcomes is the cellular heterogeneity whereby GBM cancer stem cells (CSCs) drive therapeutic resistance. Hence, there is an...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: De, Kuntal, Deighen, Amanda, Grubb, Treg, Summers, Matthew, Venere, Monica
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692330/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.922
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