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STEM-04. MECHANISM OF DYSREGULATION AND EFFICACY OF PHARMACOLOGICALLY TARGETING THE APC/C IN GLIOBLASTOMA

Glioblastoma (GBM) is the most lethal type of primary brain tumor with the common length of survival after diagnosis at only 12 to 15 months. One of the causes of poor patient outcomes is the cellular heterogeneity whereby GBM cancer stem cells (CSCs) drive therapeutic resistance. Hence, there is an...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: De, Kuntal, Deighen, Amanda, Grubb, Treg, Summers, Matthew, Venere, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692330/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.922
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