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IMMU-37. METABOLIC REPROGRAMMING OF THE GLIOMA MICROENVIRONMENT INHIBITS TUMOR IMMUNOSUPPRESSION

INTRODUCTION: Anti-tumor immunity in murine models of glioblastoma is potently suppressed by regulatory T-cell (Treg) accumulation within the tumor. Recent studies have highlighted that both glioma and immunosuppressive cellular subsets utilize fatty acid metabolism for survival. Inhibition of fatty...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Miska, Jason, Muroski, Megan, Rashidi, Aida, Chang, Alan, Zhang, Peng, Han, Yu, Lesniak, Maciej S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692258/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.495
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