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Anti-GITR therapy promotes immunity against malignant glioma in a murine model
Regulatory T cells (Tregs) are potently immunosuppressive cells that accumulate within the glioma microenvironment. The reduction in their function and/or trafficking has been previously shown to enhance survival in preclinical models of glioma. Glucocorticoid-induced TNFR-related protein (GITR) is...
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| Publicado no: | Cancer Immunol Immunother |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5101166/ https://ncbi.nlm.nih.gov/pubmed/27734112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1912-8 |
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